Highlights

It combines a mechanistic model of disease pathophysiology, PK/PD of a therapeutic agent, and quantitative experimental data. The resulting model can be used to run simulations to understand how drugs modify cellular networks and how they are impacted by the (patho)physiology, the significant pathways, and the impact of drug parameters and biological variance on drug efficacy and safety

In this webinar we will demonstrate how to:

• Building compartmental and mechanistic models
• Estimating parameters using Nonlinear Regression and Nonlinear mixed effects modelling
• Simulating virtual populations and ‘what if’ scenarios
• Automating tasks or creating customized analyses using scripts
• Creating Web apps to share simulation capabilities with non-modelers.